Description
This Baked Garlic Butter Shrimp Scampi is a nutrient-dense, anti-inflammatory seafood recipe packed with lean protein, heart-healthy fats, and immune-boosting garlic. Oven-baked in a rich lemon-garlic butter sauce and topped with Parmesan and fresh herbs, it’s naturally low-carb, keto-friendly, gluten-free (if using almond flour), and high-protein—perfect for a clean eating, Mediterranean-style lifestyle.
Shrimp provides selenium and omega-3 fatty acids that help reduce inflammation, while garlic and parsley offer powerful antioxidant benefits. This dish is ideal for those following a healthy weight loss meal plan, diabetic-friendly diet, or anti-inflammatory meal prep routine.
🥘 Full Recipe
⏱ Prep Time: 10 minutes
🔥 Cook Time: 12–15 minutes
🍽 Servings: 4
🛒 Ingredients
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1 ½ lbs large wild-caught shrimp (peeled & deveined)
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4 tbsp grass-fed butter (or extra-virgin olive oil for dairy-free)
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4 cloves garlic, minced
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2 tbsp fresh lemon juice
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1 tsp lemon zest
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½ tsp sea salt
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½ tsp black pepper
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½ tsp paprika
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½ tsp red pepper flakes (optional – boosts metabolism)
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½ cup freshly grated Parmesan cheese
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2 tbsp almond flour or gluten-free breadcrumbs
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2 tbsp chopped fresh parsley
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1 tbsp avocado oil (optional drizzle)
👩🍳 Instructions
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Preheat oven to 400°F (200°C).
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Arrange shrimp in a single layer in a greased baking dish.
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Melt butter and mix with garlic, lemon juice, zest, salt, pepper, paprika, and red pepper flakes.
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Pour garlic butter mixture evenly over shrimp.
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Sprinkle Parmesan and almond flour evenly on top.
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Bake for 12–15 minutes until shrimp turn pink and opaque.
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Broil 1–2 minutes for a golden, slightly crispy top.
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Garnish with fresh parsley and serve immediately.
🍽 Serving Suggestions (Healthy Pairings)
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🥦 Steamed broccoli or roasted asparagus (anti-inflammatory fiber boost)
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🥗 Mediterranean quinoa salad
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🥒 Zucchini noodles (low-carb pasta alternative)
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🍚 Cauliflower rice (keto & diabetic-friendly)
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🥖 Whole-grain sourdough (if not low-carb)
For a high-protein meal prep option, portion with roasted vegetables in airtight containers for up to 3 days.
🔄 Variations
🥑 Dairy-Free Version
Replace butter with avocado oil and skip Parmesan or use nutritional yeast.
🌶 Spicy Metabolism Booster
Add cayenne pepper and extra chili flakes.
🧀 Creamy Garlic Shrimp Bake
Stir ¼ cup Greek yogurt into the garlic butter before pouring over shrimp for added probiotics.
🍋 Mediterranean Style
Add chopped sun-dried tomatoes, olives, and oregano.
🥬 Paleo Option
Use ghee instead of butter and almond flour topping only.
🧠 Why It’s Anti-Inflammatory
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Garlic – contains allicin, known for reducing inflammatory markers
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Shrimp – rich in selenium & omega-3s
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Parsley – high in vitamin C and antioxidants
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Olive oil/avocado oil – heart-healthy monounsaturated fats
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Lemon – supports detox and immune function
This makes it ideal for those managing arthritis, autoimmune conditions, insulin resistance, or metabolic syndrome.
❓ Related Questions
Can I use frozen shrimp?
Yes. Thaw completely and pat dry before baking.
Is shrimp good for weight loss?
Absolutely. It’s low in calories and high in lean protein, helping support satiety.
Can I make this ahead of time?
Prep the garlic butter and shrimp separately. Bake just before serving.
Is this keto approved?
Yes — under 5g net carbs per serving when using almond flour.
What wine pairs well?
A dry Sauvignon Blanc or Pinot Grigio complements the lemon-garlic flavors.
🥗 Nutrition (Per Serving – Approximate)
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Calories: 320
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Protein: 32g
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Fat: 20g
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Net Carbs: 3–4g
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Fiber: 0.5g
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Omega-3s: ~250mg
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Selenium: 48% DV
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Vitamin B12: 35% DV
A high-protein, low-carb dinner recipe perfect for clean eating and blood sugar balance.
💡 Final Thoughts
This Baked Garlic Butter Shrimp Scampi is more than just comfort food—it’s a nutrient-dense, anti-inflammatory, metabolism-boosting seafood recipe that fits into modern health lifestyles like keto, Mediterranean diet, diabetic meal plans, and weight loss programs.
Baked Garlic Butter Shrimp Scampi (Anti-Inflammatory, Low-Carb, Keto-Friendly)

