Description
This anti-inflammatory roasted vegetable sheet pan recipe is a vibrant, nutrient-dense meal packed with fiber, antioxidants, healthy fats, and plant-based protein. Featuring caramelized root vegetables, Brussels sprouts, creamy feta cheese, omega-3-rich walnuts, and tart dried cranberries, it’s a perfect balance of sweet, savory, and crunchy.
Ideal for meal prep, clean eating, Mediterranean diet followers, and anti-inflammatory nutrition plans, this easy oven-roasted vegetable dish comes together on one pan with minimal cleanup and maximum flavor.
Ingredients (Serves 4)
Vegetables
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2 cups butternut squash, peeled & cubed
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2 cups Brussels sprouts, halved
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2 medium carrots, sliced lengthwise
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1 medium beet, peeled & cubed
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1 red onion, cut into wedges (optional)
Healthy Fats & Seasonings
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3 tbsp extra-virgin olive oil (anti-inflammatory fat)
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1 tsp turmeric powder
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1 tsp smoked paprika
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½ tsp ground black pepper (enhances turmeric absorption)
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1 tsp garlic powder
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1 tsp dried thyme or rosemary
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Sea salt, to taste
Toppings
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½ cup crumbled feta cheese
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â…“ cup raw walnuts, roughly chopped
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â…“ cup dried cranberries (unsweetened preferred)
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Optional: fresh parsley or dill for garnish
Instructions
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Preheat oven to 400°F (205°C). Line a large sheet pan with parchment paper.
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Prepare vegetables and place them evenly on the sheet pan.
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In a small bowl, whisk olive oil, turmeric, paprika, black pepper, garlic powder, herbs, and salt.
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Drizzle seasoning mixture over vegetables and toss until well coated.
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Roast for 30–35 minutes, flipping halfway, until vegetables are tender and caramelized.
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Remove from oven and sprinkle with feta, walnuts, and cranberries while still warm.
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Garnish with fresh herbs and serve immediately.
Why This Recipe Is Anti-Inflammatory 🧠💚
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Turmeric + olive oil help reduce chronic inflammation
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Cruciferous vegetables (Brussels sprouts) support detox pathways
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Walnuts provide omega-3 fatty acids
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Beets improve circulation and nitric oxide production
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Low-glycemic, whole-food ingredients support metabolic health
Serving Suggestions
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Serve as a standalone vegetarian main dish
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Pair with grilled salmon, baked chicken, or lentils for added protein
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Spoon over quinoa, farro, or wild rice
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Add to a Mediterranean mezze platter
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Top with a lemon-tahini or Greek yogurt dressing for extra creaminess
Recipe Variations & Substitutions
Vegan Version
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Swap feta for vegan feta or cashew cheese
Keto / Low-Carb
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Replace squash with cauliflower or zucchini
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Omit cranberries or use sugar-free dried berries
Paleo / Whole30
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Skip feta and add toasted pumpkin seeds
Seasonal Swaps
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Sweet potatoes, parsnips, cauliflower, or broccoli
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Pomegranate seeds instead of cranberries
Nutrition Information (Approx. Per Serving)
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Calories: 320
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Protein: 9g
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Carbohydrates: 34g
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Fiber: 8g
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Healthy Fats: 18g
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Sugar: 9g
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Sodium: Moderate
Rich in vitamin A, vitamin C, vitamin K, magnesium, polyphenols, and antioxidants
Frequently Asked Questions
Is this good for inflammation and joint pain?
Yes. This recipe includes several foods clinically associated with reduced inflammation.
Can I meal prep this?
Absolutely. Store in an airtight container for up to 4 days. Reheat at 350°F.
Is feta cheese anti-inflammatory?
In moderation, yes—especially sheep or goat feta, which is easier to digest.
Can I freeze it?
Vegetables can be frozen, but add feta and nuts fresh for best texture.
Final Thoughts 🌿
- This anti-inflammatory roasted veggie sheet pan meal is proof that healthy eating can be bold, comforting, and satisfying. It’s perfect for anyone looking to reduce inflammation naturally, support gut health, and enjoy a colorful, nutrient-packed plate without spending hours in the kitchen.

