Anti-Inflammatory Sheet Pan Chicken Fajitas
📖 Description
These Anti-Inflammatory Sheet Pan Chicken Fajitas are a vibrant, nutrient-dense, and gut-friendly twist on a classic Tex-Mex favorite. Made with lean chicken breast, colorful bell peppers, heart-healthy olive oil, and a powerful blend of anti-inflammatory spices like turmeric, cumin, and smoked paprika, this one-pan dinner is perfect for clean eating, weight management, and anti-inflammatory meal planning.
This easy sheet pan dinner is gluten-free, dairy-free, and ideal for anyone following a Mediterranean diet, anti-inflammatory diet, or looking for healthy meal prep recipes.
🛒 Ingredients (Serves 4)
Protein
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1 ½ lbs organic boneless, skinless chicken breasts (sliced into strips)
Vegetables
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1 red bell pepper, sliced
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1 yellow bell pepper, sliced
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1 green bell pepper, sliced
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1 large red onion, sliced
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2 cloves garlic, minced
Anti-Inflammatory Spice Blend
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1 ½ tsp ground turmeric
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1 tsp smoked paprika
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1 tsp ground cumin
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½ tsp chili powder
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½ tsp dried oregano
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¼ tsp black pepper (enhances turmeric absorption)
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½ tsp sea salt (or to taste)
Healthy Fats
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2 tbsp extra virgin olive oil
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Juice of 1 fresh lime
Optional Garnish
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Fresh cilantro
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Sliced avocado
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Hemp seeds or pumpkin seeds
👩🍳 Instructions
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Preheat Oven to 400°F (200°C). Line a large sheet pan with parchment paper.
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Prepare the Spice Mix by combining turmeric, paprika, cumin, chili powder, oregano, salt, and pepper.
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Season the Chicken & Veggies
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Place sliced chicken, peppers, onion, and garlic on the sheet pan.
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Drizzle with olive oil and lime juice.
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Sprinkle spice mix evenly. Toss until well coated.
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Spread Evenly into a single layer for proper roasting.
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Bake for 20–25 minutes, until chicken reaches 165°F internally.
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Optional: Broil for 2–3 minutes for lightly charred edges.
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Garnish with fresh cilantro and serve immediately.
🍽️ Serving Suggestions
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Serve in gluten-free tortillas or almond flour wraps
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Over cauliflower rice for a low-carb meal
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On top of a quinoa bowl for added fiber
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As a high-protein meal prep bowl with avocado and leafy greens
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In lettuce wraps for a keto-friendly option
🔄 Healthy Variations
🥑 Keto Version
Skip tortillas and serve over zucchini noodles or cauliflower rice.
🌱 Vegan Option
Replace chicken with:
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Portobello mushrooms
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Chickpeas
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Extra-firm tofu
🔥 Spicy Metabolism Boost
Add:
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Fresh jalapeños
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Cayenne pepper
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Chipotle powder
🥗 Mediterranean Style
Add:
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Cherry tomatoes
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Kalamata olives
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Dairy-free tzatziki
❓ Related Questions People Ask
1. Are fajitas anti-inflammatory?
Yes, when made with lean protein, healthy fats, and anti-inflammatory spices like turmeric and olive oil.
2. Is this recipe good for weight loss?
Absolutely. It’s high-protein, fiber-rich, and low in processed carbs—great for metabolic health.
3. Can I meal prep this recipe?
Yes. Store in airtight containers for up to 4 days in the refrigerator.
4. Can I freeze sheet pan chicken fajitas?
Yes, freeze in portions for up to 2 months.
5. What makes turmeric anti-inflammatory?
Curcumin, the active compound in turmeric, supports immune health and reduces oxidative stress.
🥗 Nutrition (Per Serving – Approximate)
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Calories: 320
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Protein: 38g
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Carbohydrates: 14g
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Fiber: 4g
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Fat: 14g
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Saturated Fat: 2g
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Sugar: 6g
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Sodium: 420mg
✔ High Protein
✔ Gluten-Free
✔ Dairy-Free
✔ Low Carb Option Available
✔ Anti-Inflammatory Ingredients
💡 Why This Recipe Supports an Anti-Inflammatory Lifestyle
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Turmeric + Black Pepper → Enhanced curcumin absorption
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Olive Oil → Rich in monounsaturated fats
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Bell Peppers → High in vitamin C & antioxidants
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Lean Chicken Breast → Supports muscle health
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Garlic & Onions → Natural immune support
This recipe aligns with Mediterranean diet principles, supports gut health, and helps reduce chronic inflammation.
🌟 Final Thoughts
These Anti-Inflammatory Sheet Pan Chicken Fajitas are the perfect balance of flavor, nutrition, and convenience. Whether you’re focused on clean eating, hormone balance, heart health, or simply looking for a healthy dinner recipe that’s family-friendly, this one-pan meal delivers.

